Belief in predestination is nothing but the penetration of God's decree into your own personal life; or, if you prefer it, the personal heroism to apply the sovereignty of God's decreeing will to your own existence. It means that we are not satisfied with a mere profession of words, but that we are willing to stand by our confession in regard both to this life and the life to come. It is a proof of honesty, unmovable firmness and solidity in our expressions concerning the unity of God's will, and the certainty of his operations. It is a deed of high courage because it brings you under the suspicion of high-mindedness. But if you now proceed to the decree of God, what else does God's fore-ordination mean than the certainty that the existence and course of all things, i.e., of the entire cosmos, instead of being a plaything of caprice and chance, obeys law and order, and that there exists a firm will which carries out its designs both in nature and in history?
Quote from "Calvinism and Science," Lectures on Calvinism